Postsynaptic Trafficking of AMPA Receptors: Role of SNAREs and Rab Effector Proteins
By Sandra Jurado, PhD
Postsynaptic Trafficking of AMPA Receptors: Role of SNAREs
and Rab Effector Proteins
Sandra Jurado, PhD
Assistant Professor in Pharmacology, University of Maryland Medical School
Scientific Bio: Dr. Jurado obtained her Ph.D. in Biochemistry and Molecular Biology at the Universidad Complutense in 2005. Her long-standing interest in cognition and learning lead her to undertake postdoctoral training at the University of Michigan, where she used whole-cell electrophysiology and viral-based gene delivery to identify a new role for the tumor suppressor phosphatase PTEN in hippocampal synaptic plasticity (Jurado et al., EMBO Journal2010). She then continued her postdoctoral studies on synaptic transmission and neural plasticity at Stanford University (Jurado et al., Nat Neuroscience2010). In collaboration with Dr. Thomas Südhof, she also identified the postsynaptic SNARE fusion machinery involved in AMPA-type glutamate receptor (AMPAR) insertion during long-term synaptic potentiation (Jurado et al., Neuron 2013). Dr. Jurado is currently a faculty member at the University of Maryland Department of Pharmacology. Her laboratory is focused in dissecting the molecular apparatus that underlies information processing and storage in the brain. In particular, her research seeks to elucidate the molecules involved in synaptic transmission and plasticity, as well as how these processes are regulated by neuromodulators such as endogenous neuropeptides. To achieve these goals, she uses a multidisciplinary approach including molecular and genetic manipulations, electrophysiological recordings and imaging techniques.
Place: Aula Magna, Facultat de Medicina, Casanova, 143