Neuroimmunology Program - IDIBAPS


Chloë Grace Moretz’s Descent into Madness in “Brain on Fire”


On May 1, 2014, Deadline reported that Charlize Theron had acquired the film rights to the Susannah Cahalan's 2012 memoir Brain on Fire: My Month of MadnessDakota Fanning was set to play Cahalan, a young woman who one day wakes up in a hospital with no memory of the events of the previous month. Theron would produce along with Beth Kono and A.J. Dix through her banner Denver and Delilah Productions. On January 22, 2015, Gerard Barrett was set to write and direct the adaptation, while Rob Merilees of Foundation Features would also produce and finance the film. London-based Mister Smith Entertainment sold the film to international distributors at 2015 Berlin Film FestivalWill Poulter was added to the cast on February 4, 2015, to play the boyfriend of Cahalan. On May 26, 2015, Thomas Mann and Jenny Slate were reportedly in talks to join the film, where Mann would play Cahalan's boyfriend, replacing Poulter. On June 26, 2015, it was announced that Fanning left the project due to scheduling issues, and Chloë Grace Moretz replaced her for the lead role. On July 7, 2015, it was announced that Broad Green Pictures came on board to produce and finance the film and to distribute the film in the United States, while Lindsay Macadam would also produce along with producing partner Merilees. On July 16, 2015, Carrie-Anne Moss and Richard Armitage were cast as Cahalan's parents, Rhona Nack and Tom Cahalan, respectively. On July 20, 2015, Tyler Perry joined the film to play Richard, Cahalan's boss at the New York Post.


Principal photography on the film began on July 13, 2015 in Vancouver, British Columbia. Moretz was spotted filming at the Vancouver General Hospital. On July 18, Moretz was filming a scene of near-miss by a taxicab and the Vancouver street was transformed into Manhattan. Production on the film concluded on August 10, 2015.


The film had its world premiere at the Toronto International Film Festival on September 14, 2016. Brain on fire is set to release in theatres on February 22nd, 2017.